Vicki L. Nienaber: search on Z-Library

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1

Structure determination of LpxA from the lipopolysaccharide-synthesis pathway of Acinetobacter baumannii

Badger, John, Chie-Leon, Barbara, Logan, Cheyenne, Sridhar, Vandana, Sankaran, Banumathi, Zwart, Peter H., Nienaber, Vicki

Journal:

Acta Crystallographica Section F Structural Biology and Crystallization Communications

Year:

2012

Language:

english

File:

PDF, 693 KB

english, 2012

2

Novel covalent modification of human anaplastic lymphoma kinase (ALK) and potentiation of crizotinib-mediated inhibition of ALK activity by BNP7787

Parker, Aulma, Petluru, Pavankumar, Nienaber, Vicki, Zhao, Min, Ayala, Philippe, Sridhar, Vandana, Logan, Cheyenne, Kochat, Harry, Hausheer, Frederick, Badger, John, Barbara, Chie-Leon

Journal:

OncoTargets and Therapy

Year:

2015

Language:

english

File:

PDF, 1.39 MB

english, 2015

3

Thrombin Inhibitor Design: X-Ray and Solution Studies Provide a Novel P1 Determinant

Vicki L. Nienaber, Paul D. Boxrud, Lawrence J. Berliner

Journal:

The Protein Journal

Year:

2000

Language:

english

File:

PDF, 64 KB

english, 2000

4

Automated Crystal Mounting and Data Collection for Protein Crystallography

Steven W Muchmore, Jeffrey Olson, Ronald Jones, Jeff Pan, Michael Blum, Jonathan Greer, Sean M Merrick, Peter Magdalinos, Vicki L Nienaber

Journal:

Year:

2000

Language:

english

File:

PDF, 378 KB

english, 2000

5

A glutamic acid specific serine protease utilizes a novel histidine triad in substrate binding

Nienaber, Vicki L., Breddam, Klaus, Birktoft, Jens J.

Journal:

Year:

1993

Language:

english

File:

PDF, 2.31 MB

english, 1993

6

Structure-Based Understanding of Ligand Affinity Using Human Thrombin as a Model System

Nienaber, Vicki L., Mersinger, Lawrence J., Kettner, Charles A.

Journal:

Year:

1996

Language:

english

File:

PDF, 459 KB

english, 1996

7

Cysteine Specific Targeting of the Functionally Distinct Peroxiredoxin and Glutaredoxin Proteins by the Investigational Disulfide BNP7787

Parker, Aulma, Petluru, Pavankumar, Nienaber, Vicki, Badger, John, Leverett, Betsy, Jair, Kamwing, Sridhar, Vandana, Logan, Cheyenne, Ayala, Philippe, Kochat, Harry, Hausheer, Frederick

Journal:

Year:

2015

Language:

english

File:

PDF, 2.92 MB

english, 2015

8

Discovery of Potent Inhibitors of Dihydroneopterin Aldolase Using CrystaLEAD High-Throughput X-ray Crystallographic Screening and Structure-Directed Lead Optimization

Sanders, William J., Nienaber, Vicki L., Lerner, Claude G., McCall, J. Owen, Merrick, Sean M., Swanson, Susan J., Harlan, John E., Stoll, Vincent S., Stamper, Geoffrey F., Betz, Stephen F., Condroski,

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 645 KB

english, 2004

9

Identification of Novel Binding Interactions in the Development of Potent, Selective 2-Naphthamidine Inhibitors of Urokinase. Synthesis, Structural Analysis, and SAR of N -Phenyl Amide 6-Substitution

Wendt, Michael D., Rockway, Todd W., Geyer, Andrew, McClellan, William, Weitzberg, Moshe, Zhao, Xumiao, Mantei, Robert, Nienaber, Vicki L., Stewart, Kent, Klinghofer, Vered, Giranda, Vincent L.

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 1.48 MB

english, 2004

10

Crystal Structure of ErmC‘, an rRNA Methyltransferase Which Mediates Antibiotic Resistance in Bacteria ‡

Bussiere, Dirksen E., Muchmore, Steven W., Dealwis, Christopher G., Schluckebier, Gerd, Nienaber, Vicki L., Edalji, Rohinton P., Walter, Karl A., Ladror, Uri S., Holzman, Thomas F., Abad-Zapatero, Cel

Journal:

Year:

1998

Language:

english

File:

PDF, 223 KB

english, 1998

11

Start Small and Stay Small: Minimizing Attrition in the Clinic with a Focus on CNS Therapeutics

Nienaber, Vicki

Journal:

Current Topics in Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 368 KB

english, 2009

12

Structure-directed discovery of potent non-peptidic inhibitors of human urokinase that access a novel binding subsite

Vicki L Nienaber, Donald Davidson, Rohinton Edalji, Vincent L Giranda, Vered Klinghofer, Jack Henkin, Peter Magdalinos, Robert Mantei, Sean Merrick, Jean M Severin, Richard A Smith, Kent Stewart, Karl

Journal:

Year:

2000

Language:

english

File:

PDF, 868 KB

english, 2000

13

10.1038/80319

Nienaber, Vicki L., Richardson, Paul L., Klighofer, Vered, Bouska, Jennifer J., Giranda, Vincent L., Greer, Jonathan

Journal:

Nature Biotechnology

Year:

2000

Language:

english

File:

PDF, 651 KB

english, 2000

14

Novel Inhibitors of Erm Methyltransferases from NMR and Parallel Synthesis

Hajduk, Philip J., Dinges, Jürgen, Schkeryantz, Jeffrey M., Janowick, David, Kaminski, Michele, Tufano, Michael, Augeri, David J., Petros, Andrew, Nienaber, Vicki, Zhong, Ping, Hammond, Rachel, Coen,

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 223 KB

english, 1999

15

Structure determination of LpxD from the lipopolysaccharide-synthesis pathway of Acinetobacter baumannii

Badger, John, Chie-Leon, Barbara, Logan, Cheyenne, Sridhar, Vandana, Sankaran, Banumathi, Zwart, Peter H., Nienaber, Vicki

Journal:

Acta Crystallographica Section F Structural Biology and Crystallization Communications

Year:

2013

Language:

english

File:

PDF, 571 KB

english, 2013

16

Interaction with the S1β-pocket of urokinase: 8-heterocycle substituted and 6,8-disubstituted 2-naphthamidine urokinase inhibitors

Michael D. Wendt, Andrew Geyer, William J. McClellan, Todd W. Rockway, Moshe Weitzberg, Xumiao Zhao, Robert Mantei, Kent Stewart, Vicki Nienaber, Vered Klinghofer, Vincent L. Giranda

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 421 KB

english, 2004

17

Atomic Structures of Two Nitroxide Spin Labels Complexed with Human Thrombin: Comparison with Solution Studies

Vicki L. Nienaber, Lawrence J. Berliner

Journal:

The Protein Journal

Year:

2000

Language:

english

File:

PDF, 100 KB

english, 2000

18

Probing Inhibitors Binding to Human Urokinase Crystals by Raman Microscopy: Implications for Compound Screening †

Dong, Jian, Swift, Kerry, Matayoshi, Edmund, Nienaber, Vicki L., Weitzberg, Moshe, Rockway, Todd, Carey, Paul R.

Journal:

Year:

2001

Language:

english

File:

PDF, 78 KB

english, 2001

19

Identification of Novel Inhibitors of Urokinase via NMR-Based Screening

Hajduk, Philip J., Boyd, Steven, Nettesheim, David, Nienaber, Vicki, Severin, Jean, Smith, Richard, Davidson, Don, Rockway, Todd, Fesik, Stephen W.

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 271 KB

english, 2000

20

Species Specificity of Amidine-Based Urokinase Inhibitors

Klinghofer, Vered, Stewart, Kent, McGonigal, Tom, Smith, Richard, Sarthy, Aparna, Nienaber, Vicki, Butler, Chris, Dorwin, Sarah, Richardson, Paul, Weitzberg, Moshe, Wendt, Mike, Rockway, Todd, Zhao, X

Journal:

Year:

2001

Language:

english

File:

PDF, 221 KB

english, 2001

21

Is X-ray crystallography a viable tool for lead discovery?

Journal:

Drug Discovery Today

Year:

2002

Language:

english

File:

PDF, 42 KB

english, 2002

22

Conformational similarities between one-chain and two-chain tissue plasminogen activator (t-PA): implications to the activation mechanism on one-chain t-PA

Nienaber, Vicki L., Young, Sharon L., Birktoft, Jens J., Higgins, Deborah L., Berliner, Lawrence J.

Journal:

Year:

1992

Language:

english

File:

PDF, 1.18 MB

english, 1992

23

A Noncleavable Retro-Binding Peptide That Spans the Substrate Binding Cleft of Serine Proteases. Atomic Structure of Nazumamide A: Human Thrombin ‡

Nienaber, Vicki L., Amparo, Eugene C.

Journal:

Journal of the American Chemical Society

Year:

1996

Language:

english

File:

PDF, 151 KB

english, 1996

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